Targeting Gene Regulation in Disease

our mission

To find innovative solutions for diseases of aberrant gene control by advancing the science of RNA and chromatin regulation, developing new technological platforms, and discovering early stage therapeutics.

our vision

To build a collaborative therapeutic center dedicated to excellence in studying and drugging gene regulation.


recent media & publications

Director of Chemical Biology, Dr. Calla Olson’s paper on the development of a selective CDK7 inhibitor was published in Cell Chemical Biology. Collaborators from the Nathanael Gray Lab at Dana-Farber Cancer Institute and Charles Lin Lab at Baylor College of Medicine are among contributors.

we’re hiring!

We are currently accepting applications for the following positions:
RESEARCH ASSOCIATE in diseases of gene regulation with an emphasis on cancer.

RESEARCH ASSISTANT II with background knowledge in gene regulation and expertise in mouse models

RESEARCH ASSISTANT II with a molecular biology background

upcoming events and deadlines

RNA and Chromatin Group talks are bi-weekly from September 2019-May 2020!



therapeutic innovation center at baylor college of medicine

One Baylor Plaza
MS: BCM125
Houston, TX 77030-3411

Phone: (713) 798-2133

To achieve our goal of translating fundamental discoveries in gene regulation into therapeutics, we will:

  • Align chemical biology, genomics, and computational biology for rigorous and focused therapeutic development

  • Recruit talented interdisciplinary scientists to rapidly discover new medicines

  • Bridge biological and chemical technology developments with the expertise of scientist and physicians at Baylor College of Medicine to impact diseases of altered gene control