The Therapeutic Innovation Center provides an exciting opportunity to work at the interface of academia and industry on scientific programs with direct therapeutic impact. 

We are currently hiring for the following position:

Research Assistant II

Seeking a highly motivated scientist who will support the ongoing research projects within the Therapeutic Innovation Center at BCM (THINC@BCM), a fast-paced group investigating RNA and chromatin biology to identify new oncology targets and develop first-in-class small molecule therapeutics. The ideal candidate will have extensive experience performing mammalian cell culture with a variety of cell types and growth conditions. We seek candidates with previous experience with techniques including lentiviral/retroviral production, stable cell line generation, genetic perturbations methods (RNAi and CRISPR), methods to assess cellular viability and death, flow cytometry, transfection and electroporation. Additionally, experience with standard molecular biology techniques including subcloning, vector design/construction, DNA/RNA/protein extraction, qRT-PCR and western blotting are preferred. This position requires a candidate with excellent written and oral communication skills and the ability to interact professionally with all levels of staff.

  • Working closely with THINC Group Leaders to plan, direct and conduct experiments, especially those requiring mammalian cell culture and related molecular biology.

  • Ability to identify and troubleshoot difficult problems encountered in the design/execution of projects.

  • Meticulous sterile technique and attention to detail in cell culture methods. 

  • Collecting, compiling and analyzing data.

  • Documenting and communicating results of experiments.

  • Assisting in the preparation of laboratory reports.

  • Investigating, creating and implementing new methods and technologies to improve effectiveness and efficiency.

  • Ability to work independently and effectively in a highly dynamic, multi-disciplinary environment.

  • Cleaning and maintaining laboratory equipment, supplies and work areas.

  • Maintaining laboratory organization.


  • Master's degree in a basic science or equivalent*.

  • One year of related experience.

  • *NOTE: A Bachelor's degree in a basic science and two years of directly related experience is considered equivalent to a Master's degree.

There is periodic exposure to unpleasant conditions but the work is still viewed as relatively comfortable in a laboratory environment. Frequently handles/works with biohazards or risks for potential job-related injury, such as those found in an ordinary laboratory environment.


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